Endocytosis of the Nipah Virus Glycoproteins
نویسندگان
چکیده
منابع مشابه
Interactions of human complement with virus particles containing the Nipah virus glycoproteins.
Complement is an innate immune response system that most animal viruses encounter during natural infections. We have tested the role of human complement in the neutralization of virus particles harboring the Nipah virus (NiV) glycoproteins. A luciferase-expressing vesicular stomatitis virus (VSV) pseudotype that contained the NiV fusion (F) and attachment (G) glycoproteins (NiVpp) showed dose- ...
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Nipah virus (NiV) is a member of the genus Henipavirus, which emerged in Malaysia in 1998. In pigs, infection resulted in a predominantly non-lethal respiratory disease; however, infection in humans resulted in over 100 deaths. Nipah virus has continued to re-emerge in Bangladesh and India, and person-to-person transmission appeared in the outbreak. Although a number of NiV vaccine studies have...
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7 Department of Microbiology and Immunology, Wake Forest University 8 School of Medicine, Winston-Salem, NC 27157-1064; 9 and 10 ^Department of Microbiology, Immunology and Molecular Genetics, 11 David Geffen School of Medicine, UCLA, Los Angeles, California 90095 12 13 14 15 *Corresponding Author. Mailing address: Department of Microbiology and Immunology, Wake Forest 16 University School of M...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2005
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.79.6.3865-3872.2005